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2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) Peptide

OAS1 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN939056

Aperçu rapide pour 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) Peptide (ABIN939056)

Antigène

OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

Origine

Mammifères

Source

  • 9
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Type de proteíne

    Synthetic

    Séquence

    GWRQLAQEAE AWLNYPCFKN WDGSPVSSWI LLVRPPASSL PFIPAPLHEA

    Attributs du produit

    A synthetic peptide for use as a blocking control in assays to test for specificity of OAS1 antibody,
    Alternative Names: OAS1 control peptide, OAS1 antibody Blocking Peptide, Anti-OAS1 Blocking Peptide, 2'5'-Oligoadenylate Synthetase 1 40/46Kda Blocking Peptide, IFI-4 Blocking Peptide, OIAS Blocking Peptide, OIASI Blocking Peptide, OAS1, OAS-1, OAS 1, OAS-1 Blocking Peptide, OAS 1 Blocking Peptide

    Purification

    Protein G affinity purified immunoglobulin
  • Indications d'application

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20 °C long term.
  • Antigène

    OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

    Sujet

    OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Mutations in this gene have been associated with host susceptibility to viral infection.

    Poids moléculaire

    42 kDa
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